Recombinant CD147 抗体
Quick Overview for Recombinant CD147 抗体 (ABIN7543035)
抗原
See all CD147 (BSG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD147 [OX-114], Rat IgG1, kappa
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特异性
- OX-114 binds to both the 2- and 3-domain isoforms of CD147. CD147 targets monocarboxylate transporters to the plasma membrane, and is involved in spermatogenesis, embryo implantation, neural network fomration and tumor progression. Stimulates production of matrix metalloproteases. Possibly a receptor for oligomannosidic glycans. CD147 found only in vascular endothelium in non-neoplastic regions of the brain whereas it is present in tmour cells but not in proliferating blood vessels in malignant gliomas.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- OX-114 was generated by immunizing rats with recombinant mCD147d0-2rCD4d3+4.
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亚型
- IgG1 kappa
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应用备注
- This antibody binds mouse CD147, and has been used in FC and IHC-fr analysis to characterise CD147 and detect the cell types on which it is expressed, indicating that CD147 is a lymphocyte activation marker (Paterson, 1987). This antibody failed to give immunoprecipitates from radiolabelled activated T cells.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- CD147
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背景
- Basigin, basic immunoglobulin superfamily, HT7 antigen, membrane glycoprotein gp42, gp42, gp-42, OX114, MRC OX-114, MRC OX114
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UniProt
- P18572
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途径
- S100 Proteins
抗原
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