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Recombinant CD147 抗体

This anti-CD147 antibody is a 兔 Chimeric antibody detecting CD147 in WB, FACS, IHC 和 IP. Suitable for 小鼠.
产品编号 ABIN7543034
发货至: 中国

Quick Overview for Recombinant CD147 抗体 (ABIN7543034)

抗原

See all CD147 (BSG) 抗体
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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克隆类型

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Chimeric

标记

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This CD147 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

OX-114
  • 原理

    Anti-CD147 [OX-114], Rabbit IgG, kappa

    特异性

    OX-114 binds to both the 2- and 3-domain isoforms of CD147. CD147 targets monocarboxylate transporters to the plasma membrane, and is involved in spermatogenesis, embryo implantation, neural network fomration and tumor progression. Stimulates production of matrix metalloproteases. Possibly a receptor for oligomannosidic glycans. CD147 found only in vascular endothelium in non-neoplastic regions of the brain whereas it is present in tmour cells but not in proliferating blood vessels in malignant gliomas.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    OX-114 was generated by immunizing rats with recombinant mCD147d0-2rCD4d3+4.

    亚型

    IgG kappa
  • 应用备注

    This antibody binds mouse CD147, and has been used in FC and IHC-fr analysis to characterise CD147 and detect the cell types on which it is expressed, indicating that CD147 is a lymphocyte activation marker (Paterson, 1987). This antibody failed to give immunoprecipitates from radiolabelled activated T cells.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    别名

    CD147

    背景

    Basigin, basic immunoglobulin superfamily, HT7 antigen, membrane glycoprotein gp42, gp42, gp-42, OX114, MRC OX-114, MRC OX114

    UniProt

    P18572

    途径

    S100 Proteins
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