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Recombinant CD48 抗体

This anti-CD48 antibody is a 兔 Chimeric antibody detecting CD48 in FACS 和 BP. Suitable for 大鼠.
产品编号 ABIN7543023
发货至: 中国

Quick Overview for Recombinant CD48 抗体 (ABIN7543023)

抗原

See all CD48 抗体
CD48

抗体类型

Recombinant Antibody

适用

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大鼠

宿主

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克隆类型

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Chimeric

标记

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This CD48 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Peptide (BP)

克隆位点

OX-45
  • 原理

    Anti-CD48 [OX-45], Rabbit IgG, kappa

    特异性

    OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. May be involved in the facilitation of interactions between activated lymphocytes. Likely to be involved in T cell activation.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.

    亚型

    IgG kappa
  • 应用备注

    Describes the use of OX-45 in blocking the primary mixed lymphocyte response (MLR)and the secondary response of T lymphocytes to the soluble antigen DNP-BGG. It also showed that OX-45 did not have any effect on the cytotoxic activity of specific (CTL) or non-specific (NK) killer cells or on proliferative responses stimulated by lectins or oxidative mitogenesis.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD48

    别名

    CD48

    背景

    BCM1, BCM1 surface antigen, BLAST1, BLAST-1, HM48-1, MRC OX-45 surface antigen, MRC OX45 surface antigen, OX45 surface antigen, OX-45 surface antigen, SLAM family member 2, SLAMF2, sgp60, sgp-60, signalling lymphocytic activation molecule 2 OX45, MRC OX-4

    UniProt

    P10252
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