Recombinant CD48 抗体
Quick Overview for Recombinant CD48 抗体 (ABIN7543022)
抗原
See all CD48 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Anti-CD48 [OX-45], Mouse IgG1, kappa
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特异性
 - OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. May be involved in the facilitation of interactions between activated lymphocytes. Likely to be involved in T cell activation.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
 - Protein A affinity purified
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免疫原
 - OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.
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亚型
 - IgG1 kappa
 
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应用备注
 - Describes the use of OX-45 in blocking the primary mixed lymphocyte response (MLR)and the secondary response of T lymphocytes to the soluble antigen DNP-BGG. It also showed that OX-45 did not have any effect on the cytotoxic activity of specific (CTL) or non-specific (NK) killer cells or on proliferative responses stimulated by lectins or oxidative mitogenesis.
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - PBS with 0.02 % Proclin 300.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD48
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别名
 - CD48
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背景
 - BCM1, BCM1 surface antigen, BLAST1, BLAST-1, HM48-1, MRC OX-45 surface antigen, MRC OX45 surface antigen, OX45 surface antigen, OX-45 surface antigen, SLAM family member 2, SLAMF2, sgp60, sgp-60, signalling lymphocytic activation molecule 2 OX45, MRC OX-4
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UniProt
 - P10252
 
抗原
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