Recombinant CD200R1 抗体
Quick Overview for Recombinant CD200R1 抗体 (ABIN7543015)
抗原
See all CD200R1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD200R [OX-102], Rabbit IgG, kappa
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特异性
- This antibody is specific for CD200R (OX2R), a cell-surface receptor for OX2 restricted to cells of the myeloid lineage, macrophages isolated from the peritoneal cavity, lung, spleen, and leukocyte dendritic cells are highly positive in OX102 mAb staining tests.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- 6 week-old male BALB/c mice immunized six times with either 0.1-0.25 mg of a crude Tween-40 membrane fraction solubilized from rat (PVG) thioglycollate-elicited peritoneal cells or unlysed whole cells.
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亚型
- IgG kappa
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应用备注
- This antibody binds the rat OX2 receptor, and thus can be used to stain rat resident peritoneal cells (RPCs), as well as macrophages from the lung, spleen and brain, and leukocyte dendritic cells (Wright, 2000). In addition, this antibody can be used to block the binding of OX2-coated beads to rOX2R on rat macrophages and to human kidney endothelial cells transfected with rOX2R cDNA. This antibody can also be used to purify the rOX2R antigen by immunoprecipitation from rat splenic lysates. Finally, the use of this antibody to block the OX2-OX2R interaction in rats with experimental allergic encephalomyelitis exacerbates the disease, and indicates a role for the OX2-OX2R interaction in the regulation of macrophage/microglia activity in vivo.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD200R1 (CD200 Receptor 1 (CD200R1))
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别名
- CD200R
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背景
- OX2R, CD200, OX2
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UniProt
- Q9ES58
抗原
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