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Recombinant CD200R1 抗体

This anti-CD200R1 antibody is a 兔 Chimeric antibody detecting CD200R1 in WB, FACS, IP, IHC (fro) 和 BR. Suitable for 大鼠.
产品编号 ABIN7543015
发货至: 中国

Quick Overview for Recombinant CD200R1 抗体 (ABIN7543015)

抗原

See all CD200R1 抗体
CD200R1 (CD200 Receptor 1 (CD200R1))

抗体类型

Recombinant Antibody

适用

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大鼠

宿主

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克隆类型

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Chimeric

标记

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This CD200R1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

克隆位点

OX-102
  • 原理

    Anti-CD200R [OX-102], Rabbit IgG, kappa

    特异性

    This antibody is specific for CD200R (OX2R), a cell-surface receptor for OX2 restricted to cells of the myeloid lineage, macrophages isolated from the peritoneal cavity, lung, spleen, and leukocyte dendritic cells are highly positive in OX102 mAb staining tests.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    6 week-old male BALB/c mice immunized six times with either 0.1-0.25 mg of a crude Tween-40 membrane fraction solubilized from rat (PVG) thioglycollate-elicited peritoneal cells or unlysed whole cells.

    亚型

    IgG kappa
  • 应用备注

    This antibody binds the rat OX2 receptor, and thus can be used to stain rat resident peritoneal cells (RPCs), as well as macrophages from the lung, spleen and brain, and leukocyte dendritic cells (Wright, 2000). In addition, this antibody can be used to block the binding of OX2-coated beads to rOX2R on rat macrophages and to human kidney endothelial cells transfected with rOX2R cDNA. This antibody can also be used to purify the rOX2R antigen by immunoprecipitation from rat splenic lysates. Finally, the use of this antibody to block the OX2-OX2R interaction in rats with experimental allergic encephalomyelitis exacerbates the disease, and indicates a role for the OX2-OX2R interaction in the regulation of macrophage/microglia activity in vivo.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD200R1 (CD200 Receptor 1 (CD200R1))

    别名

    CD200R

    背景

    OX2R, CD200, OX2

    UniProt

    Q9ES58
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