Recombinant CD45RC 抗体 (Extracellular Domain)
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Quick Overview for Recombinant CD45RC 抗体 (Extracellular Domain) (ABIN7543009)
抗原
See all CD45RC 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- Anti-CD45RC [OX-22], Rabbit IgG, kappa
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特异性
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OX-22 binds specifically to the high molecular weight form of the leucocyte common antigen, CD45RC. OX-22 and OX-31 compete for binding but do not compete with OX-32. The antigen is expresssed on the surface of B cells, around half of bone marrow cells, all CD8+ve T cells, and is able to differentiate between CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like) cell types. CD45 extracellular domain is able to interact with a number of different proteins including CD4, TCR, CD2, Thy-1 and CD26. CD45 is important for signalling throguh the T cell receptor and in the selection of T and B lymphocytes.
Application Notes original Clone: OX-20 can be used for both FC and IHC (paraffin/frozen) studies. It can also be used to purify proteins by affinty-purification (Woolett et al. Eur J Immunol. 1985 Feb,15(2):168-73).
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产品特性
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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纯化方法
- Protein A affinity purified
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免疫原
- OX-22 was prepared by immunizing BALB/c mice with phytohemagglutinin-activated rat lymph node cells.
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亚型
- IgG, kappa
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anti-CD45RC (CD45RC) antibody
CD45RC 适用: 大鼠 FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal OX-22 unconjugated
anti-CD45RC (CD45RC) antibody (PE)CD45RC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal GL24 PE
anti-CD45RC (CD45RC) antibodyCD45RC 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal GL24 unconjugated
anti-CD45RC (CD45RC) antibody (Biotin)CD45RC 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal GL24 Biotin
anti-CD45RC (CD45RC) antibodyCD45RC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C455-1F unconjugated
anti-CD45RC (CD45RC) antibody (FITC)CD45RC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C455-1F FITC
anti-CD45RC (CD45RC) antibody (Biotin)CD45RC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C455-1F Biotin
anti-CD45RC (CD45RC) antibody (PE)CD45RC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C455-1F PE
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD45RC
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别名
- CD45RC
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背景
- L-CA, Receptor-type tyrosine-protein phosphatase C, leukocyte common antigen, T200, CD45, OX22, MRC OX22, MRC OX-22, CD45 R
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UniProt
- P04157
抗原
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