Recombinant CD2 抗体
Quick Overview for Recombinant CD2 抗体 (ABIN7543003)
抗原
See all CD2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD2 [OX-34], Rabbit IgG, kappa
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特异性
- OX-34 binds specifically to rat CD2. CD2 is type I membrane protein involved in triggering of T-cells (cytoplasmic domain is involved in signaling function) and is expressed on thymocytes, peripheral T cells, dendritic epidermal T cells, macrophages in the spleen, and NK cells.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- OX-34 was prepared by immunizing mice with T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.
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亚型
- IgG kappa
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应用备注
- Ox34 blocks CD48 binding to CD2 causing partial block of T cell activation, OX34 can be used to deplete peripheral T cells (used to prevent allograft rejection in vivo).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD2
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别名
- CD2
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背景
- LFA-2, LFA2, OX-34 antigen, OX34 antigen, T-cell surface antigen T11/Leu5, T cell surface antigen T11/Leu5, OX34, MRC OX34, MRC OX-34
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UniProt
- P08921
抗原
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