Tyrosine Hydroxylase 抗体 (pSer40)
Quick Overview for Tyrosine Hydroxylase 抗体 (pSer40) (ABIN7540679)
抗原
See all Tyrosine Hydroxylase (TH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer40
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Supplier Product No.
- 600-401-c99
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Supplier
- Rockland
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原理
- Tyrosine Hydroxylase phospho S40 Antibody
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交叉反应 （详细）
- Expect reactivity with the following species based on sequence homology: mouse.
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纯化方法
- Anti-Tyrosine Hydroxylase pS40 antibody is affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Tyrosine Hydroxylase pS40 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 40 conjugated to KLH.
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亚型
- IgG
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anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibody
TH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibodyTH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer40) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer31) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) antibodyTH 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibodyTH 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibodyTH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer19) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 193-222), (Middle Region) antibodyTH 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (C-Term) antibodyVerified TH 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: 1:1000
IF_Microscopy_Dilution: 1:1000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Tyrosine Hydroxylase pS40 antibody is tested for use in ELISA, Western Blotting, and ICC/IHC and suitable for IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 42/44 kDa in size corresponding to the tyrosine hydroxylase proteins phosphorylated at Ser40 in the appropriate cell lysate or extract. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Tyrosine Hydroxylase (TH)
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别名
- Tyrosine Hydroxylase
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背景
- Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH,Tyrosine Hydroxylase pS40 antibody recognizes Tyrosine hydroxylase (TH) which is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs. Tyrosine Hydroxylase pS40 antibody is ideal for investigators involved in Neuronal Circuitry and disorders, and more generally in Neuroscience.
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基因ID
- 25085
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NCBI登录号
- NP_036872
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UniProt
- P04177
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途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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