KIDINS220 抗体 (pSer918)
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北京 101111
Quick Overview for KIDINS220 抗体 (pSer918) (ABIN722095)
抗原
See all KIDINS220 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer918
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Cow,Pig,Chicken,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Kidins220 around the phosphorylation site of Ser918
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亚型
- IgG
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anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1077-1370) antibody
KIDINS220 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (Internal Region) antibodyKIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (C-Term) antibodyKIDINS220 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1335-1348), (Intracellular) antibodyKIDINS220 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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别名
- Kidins220
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背景
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Synonyms: Kidins220 phospho S918, Ankyrin repeat-rich membrane-spanning protein, arms, KDIS_HUMAN, Kidins220, Kinase D interacting substance of 220 kDa, Kinase D-interacting substrate of 220 kDa, rgd 619949.
Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
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基因ID
- 57498
抗原
-
