CDK5R1 抗体 (N-Term)
Quick Overview for CDK5R1 抗体 (N-Term) (ABIN7540598)
抗原
See all CDK5R1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-me9s
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Supplier
- Rockland
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原理
- p35 Antibody
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交叉反应 （详细）
- This affinity purified antibody is directed against mouse p35/Cdk5.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
- Anti-p35/Cdk5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a near N-terminal portion of mouse p35/Cdk5 conjugated to Keyhole Limpet Hemocyanin (KLH).
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亚型
- IgG
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anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 208-307) antibody
CDK5R1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (Tyr579) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 99-307) antibodyCDK5R1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 30-64), (N-Term) antibodyCDK5R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50920 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (pSer113) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (C-Term) antibodyCDK5R1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:10,000 - 1:50,000
Immunohistochemistry_Dilution: 1:100
Western_Blot_Dilution: 1:1000
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说明
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Anti-p35/Cdk5 Antibody has been tested in ELISA, WB, and IHC. Expect bands ~34 kDa in western blot using appropriate tissues and lysates. Positive control used: mouse brain lysate in WB and IHC. This antibody is suitable in IF.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
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别名
- Cdk5r1
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背景
- Rabbit Anti-Cyclin Dependent Kinase 5 Regulatory Subunit 1 Antibody, Rabbit Anti-Cyclin-dependent kinase 5 activator 1 Antibody, Rabbit Anti-p35 Antibody, TPKII Regulatory Subunit, CDK5 Activator 1, CDK5R, NCK5A, Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (P35), Cyclin-Dependent Kinase 5 Regulatory Subunit 1, Cyclin-Dependent Kinase 5 Activator 1, Tau Protein Kinase II 23 kDa Subunit, Regulatory Partner For CDK5 Kinase, Neuronal CDK5 Activator, P35nck5a, CDK5P35, P23, P25, P35 ,p35, is a neuron specific activator of CDK5. Also known as Cdk5r1 (Cyclin-dependent kinase 5 activator 1), the complex p35/CDK5 is required for neurite outgrowth and cortical lamination. It is involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at Thr-451 and Thr-461 and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. Diseases associated with CDK5R1 include Alzheimer Disease and Non-Syndromic Intellectual Disability. Anti-p35/Cdk5 Antibody is useful for researchers interested in Alzheimer researcher, protein kinase binding, Neuroscience Research, and Cancer Research.
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基因ID
- 12569
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NCBI登录号
- NP_034001
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UniProt
- P61809
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途径
- Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
抗原
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