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CDK5R1 抗体 (N-Term)

This anti-CDK5R1 antibody is a 兔 多克隆 antibody detecting CDK5R1 in WB, ELISA 和 IHC. Suitable for 小鼠.
Rockland
产品编号 ABIN7540597
Supplier Product No.: 600-401-me9
发货至: 中国

Quick Overview for CDK5R1 抗体 (N-Term) (ABIN7540597)

抗原

See all CDK5R1 抗体
CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This CDK5R1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    N-Term

    Supplier Product No.

    600-401-me9

    Supplier

    Rockland

    原理

    p35 Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against mouse p35/Cdk5.

    纯化方法

    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-p35/Cdk5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a near N-terminal portion of mouse p35/Cdk5 conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000 - 1:50,000

    Immunohistochemistry_Dilution: 1:100

    Western_Blot_Dilution: 1:1000

    说明

    Anti-p35/Cdk5 Antibody has been tested in ELISA, WB, and IHC.  Expect bands ~34 kDa in western blot using appropriate tissues and lysates.  Positive control used: mouse brain lysate in WB and IHC. This antibody is suitable in IF.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

    别名

    Cdk5r1

    背景

    Rabbit Anti-Cyclin Dependent Kinase 5 Regulatory Subunit 1 Antibody, Rabbit Anti-Cyclin-dependent kinase 5 activator 1 Antibody, Rabbit Anti-p35 Antibody, TPKII Regulatory Subunit, CDK5 Activator 1, CDK5R, NCK5A, Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (P35), Cyclin-Dependent Kinase 5 Regulatory Subunit 1, Cyclin-Dependent Kinase 5 Activator 1, Tau Protein Kinase II 23 kDa Subunit, Regulatory Partner For CDK5 Kinase, Neuronal CDK5 Activator, P35nck5a, CDK5P35, P23, P25, P35 ,p35, is a neuron specific activator of CDK5. Also known as Cdk5r1 (Cyclin-dependent kinase 5 activator 1), the complex p35/CDK5 is required for neurite outgrowth and cortical lamination. It is involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at Thr-451 and Thr-461 and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. Diseases associated with CDK5R1 include Alzheimer Disease and Non-Syndromic Intellectual Disability. Anti-p35/Cdk5 Antibody is useful for researchers interested in Alzheimer researcher, protein kinase binding, Neuroscience Research, and Cancer Research.

    基因ID

    12569

    NCBI登录号

    NP_034001

    UniProt

    P61809

    途径

    Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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