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OPN1SW 抗体 (N-Term)

Cited in 2+ publications. The 山羊 多克隆 anti-OPN1SW antibody (ABIN7540579) specifically detects OPN1SW in ELISA 和 IHC. The antibody is reactive with 小鼠 samples.
Rockland
产品编号 ABIN7540579
Supplier Product No.: 600-101-mp7s
发货至: 中国
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Quick Overview for OPN1SW 抗体 (N-Term) (ABIN7540579)

抗原

See all OPN1SW 抗体
OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

适用

  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 10
  • 1
山羊

克隆类型

  • 11
多克隆

标记

  • 7
  • 2
  • 1
  • 1
This OPN1SW antibody is un-conjugated

应用范围

  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 3
    • 2
    N-Term

    Supplier Product No.

    600-101-mp7s

    Supplier

    Rockland

    原理

    S Opsin Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against mouse S Ospin.

    纯化方法

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-S Opsin antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal portion of mouse S Opsin conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000-1:50,000

    Immunohistochemistry_Dilution: 1:100

    说明

    Suggested Applications: IF
    Anti-S Ospin Antibody has been tested in ELISA and IHC.  Expect a band at ~39kDa in western blot using appropriate tissues and lysates.  Positive control used: Mouse eye tissue in Immunohistochemistry.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

    有效期

    12 months
  • Gupta, Młynarski, Sumser, Symonova, Svatoň, Joesch: "Panoramic visual statistics shape retina-wide organization of receptive fields." in: Nature neuroscience, Vol. 26, Issue 4, pp. 606-614, (2023) (PubMed).

    Simons, Smith, Dengler-Crish, Crish: "Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta." in: Neurobiology of disease, Vol. 147, pp. 105146, (2021) (PubMed).

  • 抗原

    OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

    别名

    Opn1sw

    背景

    Goat Anti-Short-wave-sensitive opsin 1 Antibody, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP, Short wavelength-sensitive cone opsin, Bcp, Opn1sw,Short-wave-sensitive opsin 1 belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors. Involved in ensuring correct abundance and localization of retinal membrane proteins. May increase spectral sensitivity in dim light. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. Anti-S Ospin Antibody is useful for researchers interested in Color Blindness, Metabolism of fat-soluble vitamins, and Peptide ligand-binding receptors.

    基因ID

    12057

    NCBI登录号

    NP_031564

    UniProt

    P51491
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