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OPN1SW 抗体 (N-Term)

There are 2+ publications for this product available. The 山羊 多克隆 anti-OPN1SW antibody is suitable to detect OPN1SW in samples from 小鼠. It has been validated for ELISA 和 IHC.
Rockland
产品编号 ABIN7540578
Supplier Product No.: 600-101-mp7
发货至: 中国
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Quick Overview for OPN1SW 抗体 (N-Term) (ABIN7540578)

抗原

See all OPN1SW 抗体
OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

适用

  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 10
  • 1
山羊

克隆类型

  • 11
多克隆

标记

  • 7
  • 2
  • 1
  • 1
This OPN1SW antibody is un-conjugated

应用范围

  • 7
  • 5
  • 2
  • 2
  • 1
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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 3
    • 2
    N-Term

    Supplier Product No.

    600-101-mp7

    Supplier

    Rockland

    原理

    S Opsin Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against mouse S Ospin.

    纯化方法

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-S Opsin antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal portion of mouse S Opsin conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000 - 1:50,000

    Immunohistochemistry_Dilution: 1:100

    说明

    Suggested Applications:

    Suggested_Applications: IF

    Other_Performance_Data: The 1:100 H1-20 provides optimal staining with staining of structures in multiple layers. These layers have been shown to express S-opsin in the cited reference. For staining only in the outer segment layer, the 1:200 and 1:300 H2-20 appears to be ideal.


    Anti-S Ospin Antibody has been tested in ELISA and IHC.  Expect a band at ~39kDa in western blot using appropriate tissues and lysates.  Positive control used: Mouse eye tissue in Immunohistochemistry.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • Gupta, Młynarski, Sumser, Symonova, Svatoň, Joesch: "Panoramic visual statistics shape retina-wide organization of receptive fields." in: Nature neuroscience, Vol. 26, Issue 4, pp. 606-614, (2023) (PubMed).

    Simons, Smith, Dengler-Crish, Crish: "Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta." in: Neurobiology of disease, Vol. 147, pp. 105146, (2021) (PubMed).

  • 抗原

    OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

    别名

    Opn1sw

    背景

    Goat Anti-Short-wave-sensitive opsin 1 Antibody, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP, Short wavelength-sensitive cone opsin, Bcp, Opn1sw,Short-wave-sensitive opsin 1 belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors. Involved in ensuring correct abundance and localization of retinal membrane proteins. May increase spectral sensitivity in dim light. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. Anti-S Ospin Antibody is useful for researchers interested in Color Blindness, Metabolism of fat-soluble vitamins, and Peptide ligand-binding receptors.

    基因ID

    12057

    NCBI登录号

    NP_031564

    UniProt

    P51491
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