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Doublecortin 抗体 (C-Term)

Name: Doublecortin 抗体 (C-Term)
SKU: ABIN7540561
Availability: OutOfStock

DCX 适用: 人 WB, ELISA, IHC, IF, FM 宿主: 山羊 Polyclonal unconjugated

产品编号 ABIN7540561

Supplier Product No.: 600-101-mh8

发货至: 中国

Datasheet as PDF

抗原 See all Doublecortin (DCX) 抗体

Doublecortin (DCX)
抗原表位
7

5

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
101

60

56

4

3

3

2

2

2

1

1

1

1

1
人
宿主
89

12

3

1
山羊
Compatible Secondaries
克隆类型
86

19
多克隆
标记
61

6

5

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1
This Doublecortin antibody is un-conjugated
应用范围
73

44

34

12

12

11

9

8

8

4

3

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Supplier Product No.

600-101-mh8

Supplier

Rockland

原理

Doublecortin Antibody

交叉反应（详细）

This affinity purified antibody is directed against human Neuronal migration protein doublecortin.

纯化方法

The product was affinity purified from monospecific antiserum by immunoaffinity purification.

过滤

Sterile filtered

免疫原

Anti-Doublecortin antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a near C-terminal portion of human doublecortin conjugated to Keyhole Limpet Hemocyanin (KLH).

亚型

IgG

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anti-Doublecortin (DCX) (AA 362-411) antibody
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DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Doublecortin (DCX) antibody
DCX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA_Dilution: 1:10,000-1:50,000
Immunohistochemistry_Dilution: 1:200
IF_Microscopy_Dilution: 15 μg/mL
Western_Blot_Dilution: 1:1000

说明

Anti-Doublecortin Antibody has been tested in WB, IF, and IHC. Expect bands ~40.6 kDa in western blot using appropriate lysates. Positive control used: PND2-6 brain cells in western blot, PND1 in immunofluorescence, and mouse dentate gyrus for immunohistochemistry.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
抗原

Doublecortin (DCX)

别名

DCX (DCX 产品)

背景

Goat Anti-Doublecortin Antibody, Lissencephalin-X, Doublecortex, Doublin, Lis-X, DBCN, LISX, Doublecortex Lissencephaly X-Linked (Doublecortin), Neuronal Migration Protein Doublecortin, SCLH, XLIS, DC,DCX (Neuronal Migration Protein Doublecortin) is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. In that way, it may participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. Doublecortin may be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Anti-Neuronal Migration Protein Doublecortin Antibody is useful for researcher interested in developmental biology, cytoskeletal signaling, neuroscience, and protein kinase binding.

基因ID

1641

NCBI登录号

NP_000546

UniProt

O43602