EBI3 抗体 (Biotin)
Quick Overview for EBI3 抗体 (Biotin) (ABIN7540541)
抗原
See all EBI3 (IL-27b) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 210-306-b66
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Supplier
- Rockland
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原理
- IL-35 EBI3 Biotin Conjugated Antibody
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交叉反应 （详细）
- This antibody is specific for mouse EBI3 protein.
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纯化方法
- This product was purified from mouse ascites by Protein A chromatography followed by extensive dialysis against the buffer stated above.
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免疫原
- Anti-EBI-3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.
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亚型
- IgG2b
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Labeling Ratio
- 10-20
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anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibody
IL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2-3# unconjugated
anti-Interleukin-27 subunit beta (IL-27b) antibodyIL-27b 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-227) antibodyIL-27b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibodyIL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 153-181), (C-Term) antibodyIL-27b 适用: 人 WB 宿主: 兔 Polyclonal RB30602 unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 129-229) antibodyIL-27b 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (C-Term) antibodyIL-27b 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibodyIL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1-1# unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 1-229) antibodyIL-27b 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 129-229) antibodyIL-27b 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
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应用备注
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Neutralization_Dilution: 10 μg/mL
Immunoprecipitation_Dilution: 1 μg/mL
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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This purified antibody has been tested for use in ELISA and is suitable for use in IP and Neutralization. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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别名
- Ebi3
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背景
- Mouse anti-EBI3 biotin conjugated antibody, mouse anti-IL-35 biotin conjugated antibody, Epstein-Barr virus induced 3 protein, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI-3, EBI3, IL-35, IL35,The cytokine Interleukin 27 (IL-27) is produced in response to inflammation. It is made by activated antigen presenting cells including monocytes, endothelial cells, and dendritic cells. IL-27 consists of a heterodimeric combination of Epstein-Barr virus-induced molecule 3 (EBI3, or IL-27B) non-covalently linked with IL-27 p28 (or IL-27A). It is a regulator of T helper cell development and suppressor of T-cell proliferation. IL-27 has both pro- and anti-inflammatory properties. It can stimulate cytotoxic T cell activity and induce isotype switching in B-cells. It has diverse effects on innate immune cells. It induces monocytes and mast cells to secrete pro-inflammatory cytokines. When infection is present, IL-27 induces naive CD4+ T cells to proliferate and develop Th1 cell responses. As an anti-inflammatory regulator, IL-27 can inhibit Th1 or Th2 responses and restrict the strength and duration of adaptive immune responses. The IL-27 p28 subunit, a 28 kDa glycoprotein belonging to the type I cytokine family, is homologous to IL-12 p35, IL-23 p19, and IL-6. The EBI3 (Epstein-Barr virus-induced molecule 3, or IL-27B) subunit is a 34 kDa glycoprotein containing two fibronectin type III domains, and belongs to the type I cytokine receptor family. It can exist as a homodimer and can also heterodimerize with IL-27 p28 or IL-12 p35 subunit. It is homologous to the p40 subunit of IL-12 and IL-23 and to the extracellular domain of IL-6 R.
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基因ID
- 50498
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NCBI登录号
- NP_056581
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UniProt
- O35228
抗原
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