CBX1 抗体
Quick Overview for CBX1 抗体 (ABIN7540518)
抗原
See all CBX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
Supplier Product No.
- 200-401-v35
-
Supplier
- Rockland
-
原理
- HP1 alpha, beta, gamma Antibody
-
交叉反应 (详细)
- Cross-reactivity with HP1 α, β, G from species other than human has not been determined.
-
纯化方法
- Anti-HP1 alpha, beta, gamma Antibody was purified by Protein G chromatography.
-
过滤
- Sterile filtered
-
免疫原
- Anti-HP1 alpha, beta, g Antibody was produced in rabbits by repeated immunization with a full length recombinant protein of human HP1 beta. The antibody also recognizes the alpha and gamma isoforms.
-
亚型
- IgG
-
-
-
-
应用备注
-
ChIP_Dilution: 4 μg/ChIP
IF_Microscopy_Dilution: 1:500
Western_Blot_Dilution: 1:1,000
-
说明
-
Anti-HP1 α, β, g Antibody is tested in Western blot and suitable for Chromatin Immunoprecipitation and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 20 kDa (bands for the alpha, beta, and gamma isoforms are slightly different) in the appropriate cell lysate or extract.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300 -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- CBX1 (Chromobox Homolog 1 (CBX1))
-
别名
- CBX1
-
背景
- Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1-beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25 beta,HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the innernuclear membrane. Anti-HP1 α, β, g Antibody is ideal for research in Chromatin Remodeling and Epigenetics.
-
基因ID
- 10951
-
NCBI登录号
- NP_001120700
-
UniProt
- P83916
抗原
-