FGF13 抗体 (AA 2-18) (FITC)
Quick Overview for FGF13 抗体 (AA 2-18) (FITC) (ABIN7540502)
抗原
See all FGF13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-18
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Supplier Product No.
- 200-302-w62
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Supplier
- Rockland
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原理
- FGFA/FHFA (pan) Antibody Fluorescein
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交叉反应 (详细)
- BLAST analysis suggests that it is 94 % identical to mouse, 100 % identical to rat and >80 % identical to FGF12A/FHF1A, FGF14A/FHF4A, and FGF11A/FHF3A.
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纯化方法
- Anti-FGFA/FHFA (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-FGFA/FHFA (pan) Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 2-18 of human FHF2A.
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亚型
- IgG2b
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000
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说明
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Anti-FGFA/FHFA (pan) FITC Conjugated Antibody is tested for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~30 kDa on specific lysates or tissues. Does not cross react with FGF13B/FHF2B. Will cross react with FGF12A/FHF1A and FGF14A/FHF4A. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- FGF13 (Fibroblast Growth Factor 13 (FGF13))
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别名
- FGF13
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背景
- Acidic fibroblast growth factor, AFGF, Beta endothelial cell growth factor, Fibroblast growth factor homologous factor 2A, Fibroblast growth factor 13A, FGF13A, Beta-endothelial cell growth factor, ECGF, ECGFA antibody, ECGFB, FHF-2, FHF2, FHF13, Fibroblast growth factor homologous factor 2, Fibroblast growth factor 13,FGF13(Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26.3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26.3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Other areas of interests and use for researchers include cancer, borjeson-forssman-lehmann syndrome, regulation of actin cytoskeleton pathways, apoptosis, GPCR pathways, TGF-Beta pathways, and Rho family GTPase pathways. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
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基因ID
- 2258
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UniProt
- Q92913
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途径
- Regulation of Cell Size
抗原
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