RUNX1 抗体
(1 reference)
Our Local Distributor
北京 101111
Quick Overview for RUNX1 抗体 (ABIN7540477)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
Supplier Product No.
- 100-401-v33
-
Supplier
- Rockland
-
原理
- AML1-ETO Antibody
-
交叉反应 （详细）
- This product reacts with human AML1-ETO.
-
纯化方法
- Anti-AML1-ETO Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
-
过滤
- Sterile filtered
-
免疫原
- Anti-AML1-ETO Antibody was produced in rabbits by repeated immunizations with a synthetic peptide of human AML1-ETO.
-
亚型
- IgG
-
-
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 150-250) antibody
RUNX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (pSer304) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 5A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 237-337) antibodyRUNX1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6C12A5 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 200-233), (Middle Region) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB15210 unconjugated
-
-
应用备注
-
ChIP_Dilution: 4 μL/ChIP
ELISA_Dilution: 1:500
Western_Blot_Dilution: 1:1,000
-
说明
-
Suggested Applications: Other
Anti-AML1-ETO Antibody has been tested in ChIP, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80 kDa in the appropriate cell lysate or extract. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300 -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
-
: "HDN-1 induces cell differentiation toward apoptosis in promyelocytic leukemia cells depending on its selective effect on client proteins of Hsp90." in: Toxicology and applied pharmacology, Vol. 417, pp. 115459, (2021) (PubMed).
-
: "HDN-1 induces cell differentiation toward apoptosis in promyelocytic leukemia cells depending on its selective effect on client proteins of Hsp90." in: Toxicology and applied pharmacology, Vol. 417, pp. 115459, (2021) (PubMed).
-
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
-
别名
- RUNX1
-
背景
- Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit,This antibody specifically recognizes the AML1 (RUNX1) (UniProtKB/Swiss-Prot entry Q01196) - ETO (RUNX1T1) (UniProtKB/Swiss-Prot entry Q06455) fusion protein that arises due to a translocation between chromosome 8 and 22. This translocation is one of the most frequent karyotypic abnormalities observed in acute myeloid leukemia. It produces a chimerical gene made up of the 5'-region of AML1and the 3'-region of ETO. The chimerical protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Anti-AML1-ETO Antibody is ideal for research in Cancer and Gene Expression.
-
基因ID
- 861
-
NCBI登录号
- NP_001001890
-
UniProt
- Q01196
抗原
-
