TCR V Alpha24-J Alpha18 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in FACS, ICC 和 IHC (fro). Suitable for 人 和 Non-Human Primate.
Quick Overview for TCR V Alpha24-J Alpha18 抗体 (ABIN7540469)
抗原
TCR V Alpha24-J Alpha18
适用
人, Non-Human Primate
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
克隆位点
6B11
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原理
- Anti-Hu TCR Valpha24-Jalpha18 Purified
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特异性
- The mouse monoclonal antibody 6B11 recognizes an extracellular epitope within V alpha 24 J alpha 18 TCR, which is expressed by invariant NK T cells (iNKT).
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纯化方法
- Purified by protein-A affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- TCR V Alpha24-J Alpha18
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别名
- TCR Valpha24-Jalpha18
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背景
- TCR alpha V24-J18 chain is a marker of invariant NK T cells (iNKT). This chain pairs mostly with TCR beta V11 chain, and together they interact with glycolipide-loaded CD1d. This interaction results in iNKT activation and cytokine production (IFN gamma, IL-4, IL-13), which takes important part in immune regulation and host response to pathogens and cancer(support of both Th1 and Th2 way), although iNKT cells represent less than 1 % of total peripheral T cells.
抗原
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