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SIGLEC10 抗体 (Extracellular Domain) (APC)

The APC-conjugated 小鼠 单克隆 anti-SIGLEC10 antibody (Clone 5G6) (ABIN7540465) specifically detects SIGLEC10 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7540465
发货至: 中国
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Quick Overview for SIGLEC10 抗体 (Extracellular Domain) (APC) (ABIN7540465)

抗原

See all SIGLEC10 抗体
SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

适用

  • 60
  • 3
  • 2
  • 1

宿主

  • 43
  • 18
  • 1
  • 1
小鼠

克隆类型

  • 44
  • 19
单克隆

标记

  • 28
  • 10
  • 7
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGLEC10 antibody is conjugated to APC

应用范围

  • 33
  • 29
  • 12
  • 7
  • 6
  • 5
  • 3
  • 1
Flow Cytometry (FACS)

克隆位点

5G6
  • 抗原表位

    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    原理

    Anti-Hu SIGLEC10 APC

    特异性

    The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    SIGLEC10 extracellular domain fused with human IgG1 Fc fragment

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

    别名

    SIGLEC10

    背景

    NCBI Full Gene Name: sialic acid binding Ig like lectin 10

    Description: SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.

    Other names: PRO940, SGL2

    Gene name: SIGLEC10

    基因ID

    89790

    UniProt

    Q96LC7
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