CD207 抗体 (PE)
Quick Overview for CD207 抗体 (PE) (ABIN7540425)
抗原
See all CD207 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD207 PE
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特异性
- The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Fusion protein of human CD207 extracellular part and IgG Fc fragment
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亚型
- IgG1 lambda
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anti-CD207 Molecule, Langerin (CD207) (AA 155-328) antibody
CD207 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1C5A1 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人, Non-Human Primate ELISA, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal LGRN-1821 unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 12D6 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 161-260) antibodyCD207 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (Internal Region) antibodyCD207 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 ELISA, Coat 宿主: 兔 Monoclonal LGRN-3136R unconjugated Recombinant Antibody
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal rLGRN-1821 unconjugated Recombinant Antibody
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- CD207
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背景
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NCBI Full Gene Name: CD207 Molecule
Description: CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.
Other names: CLEC4K, langerin
Gene name: CD207
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基因ID
- 50489
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UniProt
- Q9UJ71
抗原
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