Thrombomodulin 抗体 (APC)
Quick Overview for Thrombomodulin 抗体 (APC) (ABIN7540415)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD141 APC
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特异性
- The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- MV4-11 cell line
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亚型
- IgG1
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anti-Thrombomodulin (THBD) (AA 69-194) antibody
THBD 适用: 人 WB, IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal THBD-1591 unconjugated
anti-Thrombomodulin (THBD) (AA 200-500) antibodyTHBD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal rTHBD-1591 unconjugated Recombinant Antibody
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal THBD-1782 unconjugated
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 297-505) antibodyTHBD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C6C3 unconjugated
anti-Thrombomodulin (THBD) (AA 31-167) antibodyTHBD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 324-480) antibodyTHBD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 92-126) antibodyTHBD 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB56919 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Thrombomodulin (THBD)
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别名
- CD141
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背景
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NCBI Full Gene Name: thrombomodulin
Description: CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.
Other names: Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM
Gene name: THBD
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基因ID
- 7056
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UniProt
- P07204
抗原
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