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GPR77 抗体 (APC)

This anti-GPR77 antibody is a 小鼠 单克隆 antibody detecting GPR77 in FACS. Suitable for 人 和 Non-Human Primate.
产品编号 ABIN7540411
发货至: 中国

Quick Overview for GPR77 抗体 (APC) (ABIN7540411)

抗原

See all GPR77 抗体
GPR77 (G Protein-Coupled Receptor 77 (GPR77))

适用

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人, Non-Human Primate

宿主

  • 55
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小鼠

克隆类型

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单克隆

标记

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This GPR77 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

1D9-M12
  • 原理

    Anti-Hu C5aR2 APC

    特异性

    The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    L1.2 cells transfected with human C5aR2

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    GPR77 (G Protein-Coupled Receptor 77 (GPR77))

    别名

    C5aR2

    背景

    NCBI Full Gene Name: complement component 5a receptor 2

    Description: C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.

    Other names: C5L2, GPR77, GPF77

    Gene name: C5AR2

    基因ID

    27202

    UniProt

    Q9P296
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