PDHA1 抗体 (AA 241-390)
Quick Overview for PDHA1 抗体 (AA 241-390) (ABIN7539804)
抗原
See all PDHA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 241-390
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原理
- PDHA1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PDHA1(AA: 241-390) expressed in E. Coli.
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亚型
- IgG2a
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anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 30-390) antibody
PDHA1 适用: 人 WB, IHC, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 1-390) antibodyPDHA1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 30-390) antibodyPDHA1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (pSer293) antibodyPDHA1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (AA 223-390) antibodyPDHA1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) antibodyPDHA1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 斑马鱼, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (pSer293) antibodyPDHA1 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (C-Term) antibodyPDHA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
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别名
- PDHA1
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背景
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 43 kDa
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UniProt
- P08559
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途径
- Warburg Effect
抗原
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