TPSAB1 抗体 (AA 31-275)
Quick Overview for TPSAB1 抗体 (AA 31-275) (ABIN7539793)
抗原
See all TPSAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-275
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原理
- TPSAB1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TPSAB1 (AA: 31-275) expressed in E. Coli.
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亚型
- IgG1
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anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibody
TPSAB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C17 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A10-B5 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 19-210) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 115-233) antibodyTPSAB1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TPSAB1-1961 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 149-273) antibodyTPSAB1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
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别名
- TPSAB1
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背景
- Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
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分子量
- 30.5 kDa
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基因ID
- 7177
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UniProt
- Q15661
抗原
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