JAM3 抗体 (AA 32-241)
Quick Overview for JAM3 抗体 (AA 32-241) (ABIN7539787)
抗原
See all JAM3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 32-241
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原理
- JAM3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human JAM3 (AA: 32-241) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- JAM3 (Junctional Adhesion Molecule 3 (JAM3))
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别名
- JAM3
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背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
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分子量
- 35 kDa
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UniProt
- Q9BX67
抗原
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