Acetylcholinesterase 抗体
Quick Overview for Acetylcholinesterase 抗体 (ABIN7539781)
抗原
See all Acetylcholinesterase (AChE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ACHE Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human ACHE expressed in E. Coli.
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亚型
- IgG1
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anti-Acetylcholinesterase (AChE) (C-Term) antibody
Verified AChE 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 398-617) antibodyAChE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (C-Term) antibodyAChE 适用: 人, 大鼠, 小鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 157-332) antibodyAChE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 147-175), (N-Term) antibodyAChE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB16792 unconjugated
anti-Acetylcholinesterase (AChE) (AA 521-614) antibodyAChE 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 53-162) antibodyAChE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) antibodyAChE 适用: 人 ELISA, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 366-554) antibodyAChE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 147-175) antibodyAChE 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Acetylcholinesterase (AChE)
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别名
- ACHE
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背景
- Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. AChE activity may constitute a sensitive biomarker of RBC ageing in vivo, and thus, may be of aid in understanding the effects of transfusion.
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分子量
- 67.8 kDa
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基因ID
- 43
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UniProt
- P22303
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途径
- Skeletal Muscle Fiber Development
抗原
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