SH2B2 抗体 (AA 497-676)
Quick Overview for SH2B2 抗体 (AA 497-676) (ABIN7539759)
抗原
See all SH2B2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 497-676
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原理
- SH2B2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.
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亚型
- IgG2b
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
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别名
- SH2B2
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背景
- The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
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分子量
- 67.7 kDa
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UniProt
- O14492
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途径
- Carbohydrate Homeostasis, Brown Fat Cell Differentiation
抗原
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