SOCS3 抗体 (AA 1-225)
Quick Overview for SOCS3 抗体 (AA 1-225) (ABIN7539683)
抗原
See all SOCS3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-225
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原理
- SOCS3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SOCS3 (AA: 1-225) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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别名
- SOCS3
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背景
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
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分子量
- 24.8 kDa
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UniProt
- O14543
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
抗原
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