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Endothelin 1 抗体 (AA 18-212)

The 小鼠 单克隆 anti-Endothelin 1 antibody is suitable to detect Endothelin 1 in samples from 人 和 小鼠. It has been validated for ICC, ELISA 和 FACS.
产品编号 ABIN7539670
发货至: 中国
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Quick Overview for Endothelin 1 抗体 (AA 18-212) (ABIN7539670)

抗原

See all Endothelin 1 (EDN1) 抗体
Endothelin 1 (EDN1)

适用

  • 100
  • 43
  • 26
  • 19
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 91
  • 36
  • 2
小鼠

克隆类型

  • 93
  • 36
单克隆

标记

  • 59
  • 18
  • 13
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Endothelin 1 antibody is un-conjugated

应用范围

  • 104
  • 54
  • 36
  • 33
  • 26
  • 26
  • 16
  • 13
  • 12
  • 9
  • 9
  • 9
  • 7
  • 5
  • 3
  • 2
  • 1
Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS)

克隆位点

4E6E5
  • 抗原表位

    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-212

    原理

    EDN1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    Endothelin 1 (EDN1)

    别名

    EDN1

    背景

    This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

    分子量

    24.4 kDa

    UniProt

    P05305

    途径

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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