Endothelin 1 抗体 (AA 18-212)
Quick Overview for Endothelin 1 抗体 (AA 18-212) (ABIN7539670)
抗原
See all Endothelin 1 (EDN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 18-212
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原理
- EDN1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Endothelin 1 (EDN1)
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别名
- EDN1
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背景
- This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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分子量
- 24.4 kDa
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UniProt
- P05305
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
抗原
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