CD56 抗体 (iFluor™488)
Quick Overview for CD56 抗体 (iFluor™488) (ABIN7539483)
抗原
See all CD56 (NCAM1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD56 iFluor488 Antibody
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产品特性
- The clone Ncam12.19, a mouse monoclonal antibody, selectively binds to the human 140- kDa glycoprotein, an isoform of neural cell adhesion molecule (NCAM) known as CD56. It is a member of Immunoglobulin (Ig) superfamily. CD56 and CD16 expressing lymphocytes are primarily considered as human NK cells and NK-T cells. A subset of CD56+ NK cells play a unique functional role in the innate immune response as the primary source of NK cell-derived immunoregulatory cytokines, regulated in part by differential monokine production. CD56 is expressed in normal and as well as neoplastic human neuroendocrine tissues, certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias. Additionally, increased CD56+ lymphocyte subsets in peripheral blood are a significant predictive or prognostic factor in metastatic breast cancer.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human myotube cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- CD56
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基因ID
- 4684
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UniProt
- P13591
抗原
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