IL3RA 抗体 (PE-CF®594)
Quick Overview for IL3RA 抗体 (PE-CF®594) (ABIN7539439)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD123 PE-CF594 Antibody
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产品特性
- The clone HI12H7, a mouse monoclonal antibody, specifically targets the 70 kDa transmembrane α chain of the IL3 receptor, also known as CD123. This receptor is prominently expressed in various cells within the hematopoietic system, including hematopoietic progenitor cells, monocytes, and B-lymphocytes. CD123 plays a crucial role in regulating the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Notably, elevated levels of CD123 expression are frequently observed in a range of hematolymphoid neoplasms. These include acute myeloid leukemia, blastic plasmacytoid dendritic cell neoplasm, acute lymphoblastic leukemia, hairy cell leukemia, systemic mastocytosis, and certain types of B cells.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human IL3Ralpha transfected COS cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- CD123
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基因ID
- 3815
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NCBI登录号
- NP_000213, NP_001087241
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UniProt
- P10721
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途径
- JAK/STAT Signaling
抗原
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