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S100A1 抗体

This anti-S100A1 antibody is a 兔 多克隆 antibody detecting S100A1 in WB 和 ELISA. Suitable for 人 和 Cow.
产品编号 ABIN7538098
发货至: 中国

Quick Overview for S100A1 抗体 (ABIN7538098)

抗原

See all S100A1 抗体
S100A1 (S100 Calcium Binding Protein A1 (S100A1))

适用

  • 100
  • 34
  • 28
  • 17
  • 7
  • 4
人, Cow

宿主

  • 71
  • 40
  • 2
  • 1
  • 1

克隆类型

  • 62
  • 54
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This S100A1 antibody is un-conjugated

应用范围

  • 58
  • 56
  • 40
  • 25
  • 14
  • 13
  • 12
  • 10
  • 10
  • 4
  • 3
  • 2
  • 2
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  • 1
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  • 1
Western Blotting (WB), ELISA
  • 原理

    Rabbit polyclonal antibodies to Bovine S100

    特异性

    Specific to all isotypes (alpha:alpha, alpha:beta and beta:beta)

    交叉反应 (详细)

    May cross-react with other species

    纯化方法

    Protein A affinity column

    免疫原

    Native source protein

    亚型

    IgG, IgM
  • 应用备注

    Western blot: 0.1-1.0 μg/mL

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Glycine pH 7.2

    储存条件

    4 °C,-80 °C

    储存方法

    Short term up to 1 month at 2-8°C, long term can be held for up to five years at -70°C
  • 抗原

    S100A1 (S100 Calcium Binding Protein A1 (S100A1))

    别名

    S100

    背景

    Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes. These changes allow interactions with specific target proteins and modulate their activity. Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole

    分子量

    10668 Da (beta), 10518 Da (alpha)

    途径

    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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