Recombinant EGFR (Margetuximab Biosimilar) 抗体
The Human Chimeric anti-EGFR (Margetuximab Biosimilar) antibody is suitable to detect EGFR (Margetuximab Biosimilar) in samples from 人. It has been validated for ELISA 和 WB.
产品编号 ABIN7538064
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant EGFR (Margetuximab Biosimilar) 抗体 (ABIN7538064)
抗原
EGFR (Margetuximab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Human, 小鼠
克隆类型
Chimeric
标记
This EGFR (Margetuximab Biosimilar) antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Margetuximab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade
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产品特性
- Antibody Type: IgG1-kappa
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纯化方法
- Recombinant antibody expressed in mammalien cells and purified.
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纯度
- > 85%
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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缓冲液
- PBS buffer PH7.5
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储存条件
- -80 °C
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储存方法
- store at -80°C
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- EGFR (Margetuximab Biosimilar)
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物质类
- Biosimilar
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背景
- Margetuximab is an Fc-engineered human/mouse chimeric anti-HER2 monoclonal antibody of isotype IgG1 kappa . Margetuximab targets the same epitope on the HER2 extracellular domain and hass the same activity as trastuzumab. However, margetuximab has a higher affinity for both CD16A variants and a weaker one to the inhibitory CD32B Fc receptor, thereby resulting in more efficient antibody-dependent cell-mediated cytotoxicity (ADCC) and higher efficacy compared to trastuzumab.
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CAS-编号
- 1350624-75-7
抗原
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