Recombinant 4-1BB (Utomilumab Biosimilar) 抗体
This anti-4-1BB (Utomilumab Biosimilar) antibody is a Human 单克隆 antibody detecting 4-1BB (Utomilumab Biosimilar) in ELISA 和 WB. Suitable for 人.
Quick Overview for Recombinant 4-1BB (Utomilumab Biosimilar) 抗体 (ABIN7538049)
抗原
4-1BB (Utomilumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Human
克隆类型
单克隆
标记
This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
质量等级
Research Grade
-
-
Expression System
- Mammalian cells
-
原理
- Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
-
产品特性
- Antibody Type: IgG2 kappa
-
纯化方法
- Recombinant antibody expressed in mammalien cells and purified.
-
纯度
- > 85%
-
亚型
- IgG2
-
-
anti-4-1BB (Utomilumab Biosimilar) antibody
Research Grade 适用: 人 ELISA 宿主: Human Monoclonal unconjugated Recombinant Antibody
-
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS pH 7.5
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 4°C for short term, -20°C for long term
-
-
- 4-1BB (Utomilumab Biosimilar)
-
背景
- Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.
-
CAS-编号
- 1417318-27-4
抗原
-
You are here:
