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ITGA4 抗体 (FITC)

This anti-ITGA4 antibody is a 小鼠 单克隆 antibody detecting ITGA4 in FACS. Suitable for 人.
产品编号 ABIN7536953
发货至: 中国

Quick Overview for ITGA4 抗体 (FITC) (ABIN7536953)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGA4 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

HP1-2
  • 原理

    FITC Anti-Human CD49d Antibody [HP1/2]

    纯化方法

    Purified

    亚型

    IgG2a, kappa
  • 应用备注

    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: (ABIN7469777)

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    有效期

    12 months
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d

    背景

    CD49d,VLA-4 α chain, α4 integrin, Integrin α4 chain, ITGA4,CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

    基因ID

    3676

    UniProt

    P13612

    途径

    Integrin Complex
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