WWP1 抗体 (AA 21-120)
Quick Overview for WWP1 抗体 (AA 21-120) (ABIN720910)
抗原
See all WWP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human WWP1
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亚型
- IgG
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anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibody
WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (Internal Region) antibodyWWP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-260) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-922) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-261) antibodyWWP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (N-Term) antibodyWWP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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别名
- WWP1
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背景
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Synonyms: AIP 5, AIP5, Atropin-1-interacting protein 5, hSDRP1, nedd4 like, NEDD4-like E3 ubiquitin-protein ligase WWP1, Tiul1, WW domain containing E3 ubiquitin protein ligase 1, WW domain-containing protein 1, WWP 1, WWP1_HUMAN.
Background: WWP1 is an E3 ubiquitin ligase and belongs to a family of NEDD4-like proteins. WWP1 contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. The HECT domain of WWP1 has been implicated in regulating the localization and stability of p53 inhibition of WWP1 results in a decrease in p53 expression, whilst WWP1 mediated stabilization of p53 appears to be associated with an accumulation of cytoplasmic p53. WWP1 also negatively regulates the TGF beta tumor suppressor pathway by inactivating its molecular components (SMAD2, SMAD4 and TGFbetaR1). WWP1 has been implicated in both breast and prostate cancers.
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基因ID
- 11059
抗原
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