CD51/CD61 抗体 (PE)
Quick Overview for CD51/CD61 抗体 (PE) (ABIN7505942)
抗原
See all CD51/CD61 (ITGAV/ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD51/CD61 PE
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特异性
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
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无交叉反应
- Cow, Pig, 兔
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- A cell suspension containing osteoclasts from osteoclastomas
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亚型
- IgG1
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anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), IF (cc), IF (p), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡, 兔 FACS, IHC (fro), IHC 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 适用: 人 FACS 宿主: 小鼠 Monoclonal 23C6 FITC
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))
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别名
- CD51/CD61
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背景
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR
抗原
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