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CD39 抗体 (FITC)

This FITC-conjugated 小鼠 单克隆 anti-CD39 antibody (Clone TU66) specifically detects CD39 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7505932
发货至: 中国
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Quick Overview for CD39 抗体 (FITC) (ABIN7505932)

抗原

See all CD39 (ENTPD1) 抗体
CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD39 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

TU66
  • 原理

    Anti-Hu CD39 FITC

    特异性

    The mouse monoclonal antibody TU66, also known as Tü66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    亚型

    IgG2b kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

    别名

    CD39

    背景

    Ectonucleoside triphosphate diphosphohydrolase 1,CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.,ETDH1, LCAA, Ecto-ATPase 1, Ecto-apyrase, ENTPD1

    基因ID

    953

    UniProt

    P49961
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