CD207 抗体
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北京 101111
Quick Overview for CD207 抗体 (ABIN7505884)
抗原
See all CD207 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD207 Purified
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特异性
- The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.
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纯化方法
- Purified by protein-A affinity chromatography.
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免疫原
- Fusion protein of human CD207 extracellular part and IgG Fc fragment
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亚型
- IgG1 lambda
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应用备注
- Flow cytometry: Recommended dilution: 0.5-4 μg/mL. Extracellular and intracellular staining.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- CD207
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背景
- CD207 Molecule,CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.,CLEC4K, langerin
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基因ID
- 50489
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UniProt
- Q9UJ71
抗原
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