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Thrombomodulin 抗体

The 小鼠 单克隆 anti-Thrombomodulin antibody (Clone M80) (ABIN7505855) specifically detects Thrombomodulin in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7505855
发货至: 中国
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Quick Overview for Thrombomodulin 抗体 (ABIN7505855)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Thrombomodulin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

M80
  • 原理

    Anti-Hu CD141 Purified

    特异性

    The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.

    纯化方法

    Purified by protein-A affinity chromatography.

    免疫原

    MV4-11 cell line

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    Thrombomodulin (THBD)

    别名

    CD141

    背景

    Thrombomodulin,CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.,Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM

    基因ID

    7056

    UniProt

    P07204
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