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IL3RA 抗体 (PerCP)

This anti-IL3RA antibody is a 小鼠 单克隆 antibody detecting IL3RA in FACS. Suitable for 人.
产品编号 ABIN7505853
发货至: 中国

Quick Overview for IL3RA 抗体 (PerCP) (ABIN7505853)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL3RA antibody is conjugated to PerCP

应用范围

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Flow Cytometry (FACS)

克隆位点

6H6
  • 原理

    Anti-Hu CD123 PerCP

    特异性

    The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.

    纯化方法

    Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    CD123

    背景

    Interleukin 3 receptor subunit alpha,CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.,IL3RA, MGC34174, hIL-3Ra

    基因ID

    3563

    UniProt

    P26951

    途径

    JAK/STAT Signaling
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