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LIFR 抗体

LIFR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 12D3 unconjugated
产品编号 ABIN7505850
发货至: 中国
  • 抗原 See all LIFR 抗体
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    适用
    • 38
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    宿主
    • 53
    • 6
    小鼠
    克隆类型
    • 54
    • 5
    单克隆
    标记
    • 28
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    • 1
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    • 1
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    This LIFR antibody is un-conjugated
    应用范围
    • 46
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    Anti-Hu CD118 Purified
    特异性
    The mouse monoclonal antibody 12D3 recognizes an extracellular epitope of CD118, a transmembrane glycoprotein, which associates with CD130 to form the functional high affinity LIF receptor.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    human recombinant soluble CD118-Fc
    克隆位点
    12D3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LIFR Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 2-5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    别名
    CD118 (LIFR 产品)
    别名
    A230075M04Rik antibody, AW061234 antibody, LIF antibody, CD118 antibody, LIF-R antibody, SJS2 antibody, STWS antibody, SWS antibody, leukemia inhibitory factor receptor antibody, LIF receptor alpha antibody, leukemia inhibitory factor receptor alpha antibody, Lifr antibody, LOC397451 antibody, LIFR antibody
    背景
    LIF receptor subunit alpha,CD118 (LIFR alpha) is a type I transmembrane glycoprotein of the cytokine receptor family, which associates noncovalently with CD130 to form the functional high affinity LIF receptor, which also acts as an oncostatin M receptor. CD118 alone binds LIF with low affinity. A secreted form of CD118 results from alternative splicing, and may have inhibitory effect, as it also binds LIF, although with low affinity. CD118 is not expressed on lymphocytes, but it is widely expressed outside the immune system. Soluble CD118 level rises during pregnancy, in parallel with a drop in circulating LIF levels.,LIFR alpha, SWS, SJS2, STWSm, gp190
    基因ID
    3977
    UniProt
    P42702
    途径
    JAK/STAT Signaling, Growth Factor Binding
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