AGPS 抗体 (AA 158-384) (APC)
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北京 101111
Quick Overview for AGPS 抗体 (AA 158-384) (APC) (ABIN7505837)
抗原
See all AGPS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 158-384
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原理
- Anti-AGPS APC
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特异性
- The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- recombinant human AGPS (amino acids 158-384)
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亚型
- IgG2a
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- AGPS (Alkylglycerone Phosphate Synthase (AGPS))
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别名
- AGPS
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背景
- Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY
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基因ID
- 8540
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UniProt
- O00116
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途径
- SARS-CoV-2 Protein Interactome
抗原
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