Recombinant MAGEA3 抗体
Quick Overview for Recombinant MAGEA3 抗体 (ABIN7487738)
抗原
See all MAGEA3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-MAGEA3 [21B4], Rabbit IgG, kappa
-
特异性
- This antibody binds human MAGEA3 and MAGEA6, but does not cross react with other members of the MAGE family like MAGE-A1, MAGE-A4 and MAGE-A10. MAGE-A3 is a tumor specific antigen and it is expressed on many tumors like melanoma, non-small cell lung cancer, hematologic malignancies, and others.
-
产品特性
-
Original Species of Ab: Human
Original Format of Ab: IgG1
-
纯化方法
- Protein A affinity purified
-
免疫原
- The original antibody was isolated from a patient suffering from a tumor expressing a tumor specific antigen like MAGE-A3.
-
亚型
- IgG kappa
-
-
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 44-114) antibody
MAGEA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D10 unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 2-104) antibodyMAGEA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) antibodyMAGEA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 283-314), (C-Term) antibodyMAGEA3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB2084 unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 44-114) antibodyMAGEA3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 216-265) antibodyMAGEA3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 1-314) antibodyMAGEA3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 44-114) antibodyMAGEA3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) antibodyMAGEA3 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Melanoma Antigen Family A, 3 (MAGEA3) antibodyMAGEA3 适用: 人 WB 宿主: 小鼠 Monoclonal 2E11 unconjugated
-
-
应用备注
- The binding specificity of this antibody towards MAGE-A3 was determined using ELISA. The original antibody cross reacts with MAGEA6 but does not react with other members of the MAGE family in an ELISA or western blot assay. This antibody was used in the detection of HEK293T cells expressing MAGEA3 and MAGEA6 using flow cytometry. The original IgG1 antibody was capable of immunoprecipitating MAGE-A3 from lysates of SK-MEL-37 cells endogenously expressing MAGEA3. The original antibody was also used in the immunohistochemical staining of tissues form normal testis and squamous cell carcinoma of the lung (US20140093514).
-
说明
-
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))
-
别名
- MAGEA3
-
背景
- MAGE-3, MAGE3, MAGE 3, CT1.3, MAGE-3 antigen, Melanoma-associated antigen 3, Antigen MZ2-D, Cancer/testis antigen 1.3, MAGEA6, MAGE6, Melanoma-associated antigen 6, Cancer/testis antigen 1.6, CT1.6, MAGE-6 antigen, MAGE3B antigen
-
UniProt
- P43357, P43360
抗原
-
