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Recombinant CD47 抗体

This anti-CD47 antibody is a 大鼠 单克隆 antibody detecting CD47 in IF 和 BP. Suitable for 人.
产品编号 ABIN7487702
发货至: 中国

Quick Overview for Recombinant CD47 抗体 (ABIN7487702)

抗原

See all CD47 抗体
CD47

抗体类型

Recombinant Antibody

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This CD47 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Blocking Peptide (BP)

克隆位点

MIAP430
  • 原理

    Anti-CD47 [mIAP430], Rat IgG2a, kappa

    特异性

    This antibody recognises CD47 which is a a multitransmembrane glycoprotein widely expressed on all hematopoietic cells and most other cell types. It is involved in cell adhesion, Ca2+ influx, platelet activation and peripheral mononuclear neutrophils migration across endothelial and epithelial monolayers.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunising IAP-deficient mice with purified human placental CD47.

    亚型

    IgG2a kappa
  • 应用备注

    This antibody can be used to investigate the role of the CD47 receptor. mIAP430 was first used to visualise the distribution of CD47 on fusing macrophages (Han et al., 2000). Further, it was demonstrated that this antibody can block fusion of macrophages by blocking CD47 and preventing the binding of this receptor with MFR (Han et al., 2000).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD47

    别名

    CD47

    背景

    IAP, C5/D5, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6

    UniProt

    Q08722
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