Recombinant Varicella Zoster Virus gE (VZV gE) 抗体 (Biotin)
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Quick Overview for Recombinant Varicella Zoster Virus gE (VZV gE) 抗体 (Biotin) (ABIN7488728)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Biotinylated Monoclonal Anti-Glycoprotein E (VZV) Antibody, Human IgG1 (4G2)
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亚型
- IgG1
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C
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- Varicella Zoster Virus gE (VZV gE)
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别名
- VZV gE
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物质类
- Viral Protein
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背景
- Varicella-zoster virus (VZV) is a neurotropic virus belonging to the Herpesviridae family. Primary VZV infection causes chickenpox and is followed by a life-long latent infection established mainly in the cranial and dorsal root ganglia. Reactivation of the virus is often associated with shingles (herpes zoster). Glycoprotein E (gE) is one of the known glycoproteins (gB, gC, gE, gH, gI, gK, gI) of VZV that is most abundantly expressed on the surface of virus and infected cells, playing an important role in viral replication and cell-to-cell spread. The strongly immunogenic gE can provide strong IgG signal in body fluid, which makes it ideal to be developed as an antigen for analysis of IgG antibodies. gE also demonstrates high potency as a vaccine immunogen and is formulated as the single viral envelope protein that constitutes the GSK VZV recombinant subunit vaccine Shingrix®.The antibody can reacte with gE specially.
抗原
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