Quick Overview for Recombinant Trastuzumab 抗体 (ABIN7482306)
抗原
Trastuzumab
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
克隆位点
AY1b
原理
Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)
产品特性
Anti-idiotypic Antibodies
免疫原
Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
限制
仅限研究用
状态
Lyophilized
储存条件
-20 °C
抗原
Trastuzumab
背景
Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.