Quick Overview for Recombinant Bevacizumab 抗体 (ABIN7482170)
抗原
Bevacizumab
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This Bevacizumab antibody is un-conjugated
质量等级
MALS verified
克隆位点
AY10
原理
Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)
产品特性
Anti-idiotypic Antibodies
免疫原
Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.